Product line
FERMI SKID BF50 bioreactor
A self-contained bioreactor for bacteriophage production: integrated CIP and SIP, a clean room design and fully GMP-compliant software with flexible recipe management — ideal for pilot-scale production and R&D laboratories.
- Key figure
- Integrated CIP and SIP
- Industries
- Biopharma
What it does
Not just a bioreactor — an innovation
As antibiotics face declining efficacy, the need for innovative solutions is vital. RENI’s answer for bacteriophage production is the FERMI SKID BF50 — a bioreactor designed to transform how bacteriophages are produced, as biopharmaceutical development grows in importance in the face of new healthcare challenges.
The unit is self-contained. Clean-in-place and sterilise-in-place systems are integrated for optimal hygiene at every step, and purified water is dosed automatically, directly from the loop. The hygienic design starts with the exterior — the frame and the cable trays — and extends to a clean-design electrical cabinet.
Fully GMP-compliant software runs the process with audit trails, archives and reports; its flexible recipe management makes the BF50 ideal for pilot-scale production and R&D laboratories.
Features
Key features
- Integrated CIP and SIP systems for optimal hygiene at every step
- Automated purified water dosing, directly from the loop with an air-brake valve
- Clean room design, from the frame and cable trays to the electrical cabinet
- Fully GMP-compliant software with audit trails, archives, reports and recipe management
- Bottom-mounted, magnetically coupled agitator for optimal mixing
- Digital load cells with capacitive technology and a hygienic design
- New-generation hygienic membrane valves that accelerate CIP cycles
- CLIP ON temperature sensors for sterilisation control
- Pneumatic lid lift, CIP cleaning of the filter housings, double filter group with automatic switchover
Specification
Technical data
- Application
- Bacteriophage production; pilot-scale production and R&D laboratories
- Cleaning
- Integrated CIP and SIP; CIP cleaning of the filter housings
- Purified water
- Automated dosing from the PW loop, with an air-brake valve
- Agitation
- Bottom-mounted, magnetically coupled agitator
- Weighing
- Digital load cells, capacitive technology, hygienic design
- Control
- Fully GMP-compliant software: audit trails, archives, reports, flexible recipe management
- Working volume
- On enquiry
Values as published by RENI. The figures for your system are defined with you and confirmed in the offer.
Where it is used
Applications and references
RENI names these industries as relevant for its bioreactors: biotechnology, pharmaceuticals (antibiotics, vaccines), food and beverages, nutraceuticals, probiotics, cosmeceuticals, chemicals, agriculture, biofuels, bioremediation, and animal health and nutrition.
Reference projects for this line are named on request.
In pictures
Details of the system
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